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SMILES: FC1CC(C1)NC(=O)c1nc2cccnc2n1-c1ccc(Cl)c(Cl)c1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50561534   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50561534
PNG
(CHEMBL4765220)
Show SMILES FC1CC(C1)NC(=O)c1nc2cccnc2n1-c1ccc(Cl)c(Cl)c1 |(66.16,-23.92,;64.62,-23.93,;63.54,-25.02,;62.45,-23.94,;63.53,-22.84,;60.91,-23.95,;60.13,-22.62,;60.89,-21.28,;58.59,-22.63,;57.69,-23.88,;56.22,-23.41,;54.88,-24.19,;53.54,-23.42,;53.55,-21.88,;54.87,-21.11,;56.21,-21.87,;57.67,-21.39,;58.14,-19.93,;57.11,-18.79,;57.57,-17.33,;59.08,-16.99,;59.54,-15.52,;60.12,-18.13,;61.62,-17.8,;59.65,-19.6,)|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 600n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...

Citation and Details

Article DOI: 10.1021/acsmedchemlett.9b00369
BindingDB Entry DOI: 10.7270/Q2WM1J4P
More data for this
Ligand-Target Pair