null

SMILES: O=c1ccoc2ccc(OCCCN3CCCCCC3)cc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50562062   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50562062 (CHEMBL4754186) Show SMILES O=c1ccoc2ccc(OCCCN3CCCCCC3)cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]pentazocine from human sigma 1 receptor expressed in HEK293 cell membrane incubated for 2 hrs by liquid scintillation counting me...				Citation and Details Article DOI: 10.1039/d1md00105a BindingDB Entry DOI: 10.7270/Q2125XB5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50562062 (CHEMBL4754186) Show SMILES O=c1ccoc2ccc(OCCCN3CCCCCC3)cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114464 BindingDB Entry DOI: 10.7270/Q2FB56XK
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50562062 (CHEMBL4754186) Show SMILES O=c1ccoc2ccc(OCCCN3CCCCCC3)cc12 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of (+)-[3H]DTG from sigma 2 receptor in SPRD rat liver membrane incubated for 2 hrs by liquid scintillation counting method				Citation and Details Article DOI: 10.1039/d1md00105a BindingDB Entry DOI: 10.7270/Q2125XB5
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50562062 (CHEMBL4754186) Show SMILES O=c1ccoc2ccc(OCCCN3CCCCCC3)cc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114464 BindingDB Entry DOI: 10.7270/Q2FB56XK
					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50562062 (CHEMBL4754186) Show SMILES O=c1ccoc2ccc(OCCCN3CCCCCC3)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114464 BindingDB Entry DOI: 10.7270/Q2FB56XK
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50562062 (CHEMBL4754186) Show SMILES O=c1ccoc2ccc(OCCCN3CCCCCC3)cc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human AChE				Citation and Details Article DOI: 10.1039/d1md00105a BindingDB Entry DOI: 10.7270/Q2125XB5
					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50562062 (CHEMBL4754186) Show SMILES O=c1ccoc2ccc(OCCCN3CCCCCC3)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human BuChE				Citation and Details Article DOI: 10.1039/d1md00105a BindingDB Entry DOI: 10.7270/Q2125XB5
					More data for this Ligand-Target Pair