null

SMILES: CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccc(OCC#C)cc1)C1Cc2ccccc2C1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50562766   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50562766 (CHEMBL4794870) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccc(OCC#C)cc1)C1Cc2ccccc2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]raclopride from human D2R isoform 2 stably expressed in HEK293 cell membranes measured after 1 hr by liquid scintillation countin...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.113151 BindingDB Entry DOI: 10.7270/Q2988BR6
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50562766 (CHEMBL4794870) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccc(OCC#C)cc1)C1Cc2ccccc2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	321	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human D2R isoform 2 stably expressed in HEK293 cells assessed as inhibition of forskolin-induced increase of cAMP accumulation pr...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.113151 BindingDB Entry DOI: 10.7270/Q2988BR6
					More data for this Ligand-Target Pair