null

SMILES: Cc1nn(-c2ccccc2)c2nc(CC(=O)N3NC(=O)\C(=C/c4ccccc4)N=C3c3ccccc3)[nH]c(=O)c12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563092   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50563092 (CHEMBL4790553) Show SMILES Cc1nn(-c2ccccc2)c2nc(CC(=O)N3NC(=O)\C(=C/c4ccccc4)N=C3c3ccccc3)[nH]c(=O)c12 |c:30| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	872	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of HER2 (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113222 BindingDB Entry DOI: 10.7270/Q2KK9GKK
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50563092 (CHEMBL4790553) Show SMILES Cc1nn(-c2ccccc2)c2nc(CC(=O)N3NC(=O)\C(=C/c4ccccc4)N=C3c3ccccc3)[nH]c(=O)c12 |c:30| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	656	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EGFR T790M mutant (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113222 BindingDB Entry DOI: 10.7270/Q2KK9GKK
					More data for this Ligand-Target Pair