null

SMILES: ONC(=O)[C@H]1C[C@H](CN1S(=O)(=O)c1ccc(Cl)c(Cl)c1)NC(=O)c1cccs1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50563348   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50563348 (CHEMBL2088993) Show SMILES ONC(=O)[C@H]1C[C@H](CN1S(=O)(=O)c1ccc(Cl)c(Cl)c1)NC(=O)c1cccs1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of MMP9 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 5 min followed by substrate addition and...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113260 BindingDB Entry DOI: 10.7270/Q2WW7NF0
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50563348 (CHEMBL2088993) Show SMILES ONC(=O)[C@H]1C[C@H](CN1S(=O)(=O)c1ccc(Cl)c(Cl)c1)NC(=O)c1cccs1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	131	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of MMP2 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 5 min followed by substrate addition and...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113260 BindingDB Entry DOI: 10.7270/Q2WW7NF0
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50563348 (CHEMBL2088993) Show SMILES ONC(=O)[C@H]1C[C@H](CN1S(=O)(=O)c1ccc(Cl)c(Cl)c1)NC(=O)c1cccs1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA2 incubated for 15 mins by stopped-flow CO2 hydration kinetic assay based Cheng-Prusoff equation analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113260 BindingDB Entry DOI: 10.7270/Q2WW7NF0
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50563348 (CHEMBL2088993) Show SMILES ONC(=O)[C@H]1C[C@H](CN1S(=O)(=O)c1ccc(Cl)c(Cl)c1)NC(=O)c1cccs1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA1 incubated for 15 mins by stopped-flow CO2 hydration kinetic assay based Cheng-Prusoff equation analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113260 BindingDB Entry DOI: 10.7270/Q2WW7NF0
					More data for this Ligand-Target Pair