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SMILES: COc1ccc(cc1)S(=O)(=O)NCCCNc1nccc(n1)-c1[nH]c(nc1-c1ccc(F)c(O)c1)-c1ccccc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563431   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50563431 (CHEMBL4793723) Show SMILES COc1ccc(cc1)S(=O)(=O)NCCCNc1nccc(n1)-c1[nH]c(nc1-c1ccc(F)c(O)c1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of p38 alpha (unknown origin) using Ser/Thr 15 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50563431 (CHEMBL4793723) Show SMILES COc1ccc(cc1)S(=O)(=O)NCCCNc1nccc(n1)-c1[nH]c(nc1-c1ccc(F)c(O)c1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113277 BindingDB Entry DOI: 10.7270/Q2VX0M8Q
					More data for this Ligand-Target Pair