null
SMILES: NC(CSC1(c2ccc(cc2)C(F)(F)F)c2ccccc2CCc2ccccc12)C(=O)NCCO
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinesin-like protein KIF11 (Homo sapiens (Human)) | BDBM50563615 (CHEMBL4791487) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition C-terminal His-tagged KSP motor domain(1 to 369 residues) (unknown origin) expressed in bacteria assessed as inhibition of microtubule-sti... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113288 BindingDB Entry DOI: 10.7270/Q2668HXW | |||||||||||
More data for this Ligand-Target Pair |