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SMILES: Cc1ccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3[nH]ncc3c2)cc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563626   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50563626 (CHEMBL4798879) Show SMILES Cc1ccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3[nH]ncc3c2)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human GST-fused ALK5 expressed in baculovirus infected Sf9 cells assessed as incoporation of [33]Pi after 60 mins in presen...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113311 BindingDB Entry DOI: 10.7270/Q22F7S54
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50563626 (CHEMBL4798879) Show SMILES Cc1ccc(NCc2nc(c([nH]2)-c2cccc(C)n2)-c2ccc3[nH]ncc3c2)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	329	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human p38alpha expressed in Escherichia coli assessed as incoporation of [33]Pi after 60 mins in presence of [gamma-33P]-AT...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113311 BindingDB Entry DOI: 10.7270/Q22F7S54
					More data for this Ligand-Target Pair