BindingDB PrimarySearch_ki

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Enter Data

null

SMILES: CNC(=O)c1cnc(Nc2ccc(OC)cc2C)nc1NC1CCCC1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50563654
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50563654 (CHEMBL4788254) Show SMILES CNC(=O)c1cnc(Nc2ccc(OC)cc2C)nc1NC1CCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01904 BindingDB Entry DOI: 10.7270/Q2XP78NC
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM50563654 (CHEMBL4788254) Show SMILES CNC(=O)c1cnc(Nc2ccc(OC)cc2C)nc1NC1CCCC1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-tagged AXL (unknown origin) (464 to 485 residues) using Axltide (CKKSRGDYMTMQJG-acid) peptide as substrate preincubated for 30 mins...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01904 BindingDB Entry DOI: 10.7270/Q2XP78NC
TBA					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50563654 (CHEMBL4788254) Show SMILES CNC(=O)c1cnc(Nc2ccc(OC)cc2C)nc1NC1CCCC1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of His6/TEV fused-GST-tagged Flt3 (unknown origin) (H564 to S993 residues) using Axltide (CKKSRGDYMTMQJ-acid) peptide as substrate preincu...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01904 BindingDB Entry DOI: 10.7270/Q2XP78NC
TBA					More data for this Ligand-Target Pair