null
SMILES: Cl.CCCCCn1cc(nc1N)-c1ccccc1C(=O)OC
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50563762![]() (CHEMBL4796992) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.11E+4 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac... | Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00023 BindingDB Entry DOI: 10.7270/Q2CR5Z3F | |||||||||||
More data for this Ligand-Target Pair |