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SMILES: Cl.CCCCCn1cc(nc1N)-c1ccccc1C(=O)OC

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50563762   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Toll-like receptor 8


(Homo sapiens (Human))
BDBM50563762
PNG
(CHEMBL4796992)
Show SMILES Cl.CCCCCn1cc(nc1N)-c1ccccc1C(=O)OC
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.11E+4n/an/an/an/a


TBA

Assay Description
Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.6b00023
BindingDB Entry DOI: 10.7270/Q2CR5Z3F
More data for this
Ligand-Target Pair