null
SMILES: NCC(O)C(O)=O
InChI Key:
PDB links: 5 PDB IDs match this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium- and chloride-dependent GABA transporter 3 (Mus musculus) | BDBM50563978![]() (CHEMBL4798809) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mouse GAT4 expressed in HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 35 mins by liquid scintillation metho... | Citation and Details Article DOI: 10.1016/j.ejmech.2019.111920 BindingDB Entry DOI: 10.7270/Q2FJ2MJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus) | BDBM50563978![]() (CHEMBL4798809) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 2.51E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mouse GAT1 expressed in HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 35 mins by liquid scintillation metho... | Citation and Details Article DOI: 10.1016/j.ejmech.2019.111920 BindingDB Entry DOI: 10.7270/Q2FJ2MJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent GABA transporter 2 (Mus musculus) | BDBM50563978![]() (CHEMBL4798809) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 2.29E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mouse GAT2 expressed in HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 35 mins by liquid scintillation metho... | Citation and Details Article DOI: 10.1016/j.ejmech.2019.111920 BindingDB Entry DOI: 10.7270/Q2FJ2MJJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent GABA transporter 3 (Mus musculus) | BDBM50563978![]() (CHEMBL4798809) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mouse GAT3 expressed in HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 35 mins by liquid scintillation metho... | Citation and Details Article DOI: 10.1016/j.ejmech.2019.111920 BindingDB Entry DOI: 10.7270/Q2FJ2MJJ | |||||||||||
More data for this Ligand-Target Pair |