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SMILES: Cl.Oc1ccc2N\C(\C(=N\OCCN3CCOCC3)\c2c1)=C1/C(=O)Nc2ccc(cc12)[N+]([O-])=O

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50564353   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50564353
PNG
(CHEMBL4782567)
Show SMILES Cl.Oc1ccc2N\C(\C(=N\OCCN3CCOCC3)\c2c1)=C1/C(=O)Nc2ccc(cc12)[N+]([O-])=O
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 345n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant His-tagged human FLT3 expressed in baculovirus expression system using peptide substrate incubated for 30 mins in presence ...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112205
BindingDB Entry DOI: 10.7270/Q2VM4H1R
More data for this
Ligand-Target Pair