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SMILES: Cl.CN1CCN(CCO\N=C2\C(\Nc3ccccc\23)=C2\C(=O)Nc3ccc(OC(F)(F)F)cc23)CC1

InChI Key:

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50564375   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor-type tyrosine-protein kinase FLT3 [K633Q]


(Homo sapiens (Human))		BDBM50564375
PNG
(CHEMBL4795997)
Show SMILES Cl.CN1CCN(CCO\N=C2\C(\Nc3ccccc\23)=C2\C(=O)Nc3ccc(OC(F)(F)F)cc23)CC1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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DrugBank
GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.60n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant His-tagged human FLT3 expressed in baculovirus expression system using peptide substrate incubated for 30 mins in presence ...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112205
BindingDB Entry DOI: 10.7270/Q2VM4H1R
More data for this
Ligand-Target Pair