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null

SMILES: Cl.COc1ccccc1N1CCN(CCCCC(=O)Nc2ccc(cc2)C(C)C)CC1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50565201
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50565201 (CHEMBL4782285) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112437 BindingDB Entry DOI: 10.7270/Q2NS0ZP0
TBA					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50565201 (CHEMBL4782285) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	451	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112437 BindingDB Entry DOI: 10.7270/Q2NS0ZP0
TBA					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50565201 (CHEMBL4782285) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human PDE4B expressed in Sf9 cells measured after 10 mins by luminescence based assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112437 BindingDB Entry DOI: 10.7270/Q2NS0ZP0
TBA					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50565201 (CHEMBL4782285) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.51E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human PDE7A expressed in Sf9 cells measured after 10 mins by luminescence based assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112437 BindingDB Entry DOI: 10.7270/Q2NS0ZP0
TBA					More data for this Ligand-Target Pair