null
SMILES: COc1cc(OC)c2c(nc(nc2c1)-c1cc(C)c(OCCCC(=O)NO)c(C)c1)N1CCOC[C@@H]1C
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 6 (Homo sapiens (Human)) | BDBM50565527![]() (CHEMBL4790567) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human His-tagged HDAC6 expressed in baculovirus infected insect cells using Ac-Leu-Gly-Lys(Ac)-AMC as substrate measured af... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112648 BindingDB Entry DOI: 10.7270/Q2Z323DQ | |||||||||||
More data for this Ligand-Target Pair |