null
SMILES: Cn1c(nc2ccc(F)cc12)C(=O)c1c[nH]c2c(F)cccc12
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proprotein convertase subtilisin/kexin type 9 (Homo sapiens (Human)) | BDBM50565590 (CHEMBL4780905) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.150 | n/a | n/a | n/a | n/a |
TBA | Assay Description Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112678 BindingDB Entry DOI: 10.7270/Q2F193GX | |||||||||||
More data for this Ligand-Target Pair |