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SMILES: COc1ccc(cc1)C1C2COc3ccccc3C2=NN1c1ccc(cc1)C(O)=O

InChI Key:

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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50566426   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM50566426
PNG
(CHEMBL4848935)
Show SMILES COc1ccc(cc1)C1C2COc3ccccc3C2=NN1c1ccc(cc1)C(O)=O |c:21|
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.16E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant full length GST-tagged PDE5A1 (unknown origin) expressed in baculovirus infected Sf9 insect cells using TAMRA-cGMP as subst...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01120
BindingDB Entry DOI: 10.7270/Q2765K34
More data for this
Ligand-Target Pair