null

SMILES: CCCCc1[nH]c(=O)c(c(O)c1-c1c(OC)cccc1OC)S(=O)(=O)c1ccc(cc1)-c1cccnc1OC

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50567164   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apelin receptor (Homo sapiens (Human))	BDBM50567164 (CHEMBL4848436) Show SMILES CCCCc1[nH]c(=O)c(c(O)c1-c1c(OC)cccc1OC)S(=O)(=O)c1ccc(cc1)-c1cccnc1OC |(1.28,-54.76,;2.61,-55.53,;3.95,-54.76,;5.28,-55.53,;6.61,-54.76,;6.62,-53.22,;7.95,-52.45,;7.94,-50.91,;9.28,-53.21,;9.29,-54.76,;10.62,-55.53,;7.95,-55.53,;7.95,-57.07,;9.28,-57.83,;10.61,-57.06,;11.95,-57.83,;9.29,-59.37,;7.95,-60.15,;6.61,-59.38,;6.61,-57.84,;5.28,-57.07,;3.95,-57.83,;10.61,-52.43,;9.83,-51.09,;11.38,-51.09,;11.95,-53.2,;11.95,-54.74,;13.28,-55.5,;14.62,-54.73,;14.6,-53.18,;13.27,-52.42,;15.95,-55.49,;17.27,-54.71,;18.61,-55.47,;18.62,-57.02,;17.29,-57.79,;15.96,-57.03,;14.62,-57.81,;14.63,-59.35,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assay				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128325 BindingDB Entry DOI: 10.7270/Q2KD22N4
					More data for this Ligand-Target Pair
Apelin receptor (Mus musculus)	BDBM50567164 (CHEMBL4848436) Show SMILES CCCCc1[nH]c(=O)c(c(O)c1-c1c(OC)cccc1OC)S(=O)(=O)c1ccc(cc1)-c1cccnc1OC |(1.28,-54.76,;2.61,-55.53,;3.95,-54.76,;5.28,-55.53,;6.61,-54.76,;6.62,-53.22,;7.95,-52.45,;7.94,-50.91,;9.28,-53.21,;9.29,-54.76,;10.62,-55.53,;7.95,-55.53,;7.95,-57.07,;9.28,-57.83,;10.61,-57.06,;11.95,-57.83,;9.29,-59.37,;7.95,-60.15,;6.61,-59.38,;6.61,-57.84,;5.28,-57.07,;3.95,-57.83,;10.61,-52.43,;9.83,-51.09,;11.38,-51.09,;11.95,-53.2,;11.95,-54.74,;13.28,-55.5,;14.62,-54.73,;14.6,-53.18,;13.27,-52.42,;15.95,-55.49,;17.27,-54.71,;18.61,-55.47,;18.62,-57.02,;17.29,-57.79,;15.96,-57.03,;14.62,-57.81,;14.63,-59.35,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at mouse APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assay				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128325 BindingDB Entry DOI: 10.7270/Q2KD22N4
					More data for this Ligand-Target Pair
Apelin receptor (Rattus norvegicus)	BDBM50567164 (CHEMBL4848436) Show SMILES CCCCc1[nH]c(=O)c(c(O)c1-c1c(OC)cccc1OC)S(=O)(=O)c1ccc(cc1)-c1cccnc1OC |(1.28,-54.76,;2.61,-55.53,;3.95,-54.76,;5.28,-55.53,;6.61,-54.76,;6.62,-53.22,;7.95,-52.45,;7.94,-50.91,;9.28,-53.21,;9.29,-54.76,;10.62,-55.53,;7.95,-55.53,;7.95,-57.07,;9.28,-57.83,;10.61,-57.06,;11.95,-57.83,;9.29,-59.37,;7.95,-60.15,;6.61,-59.38,;6.61,-57.84,;5.28,-57.07,;3.95,-57.83,;10.61,-52.43,;9.83,-51.09,;11.38,-51.09,;11.95,-53.2,;11.95,-54.74,;13.28,-55.5,;14.62,-54.73,;14.6,-53.18,;13.27,-52.42,;15.95,-55.49,;17.27,-54.71,;18.61,-55.47,;18.62,-57.02,;17.29,-57.79,;15.96,-57.03,;14.62,-57.81,;14.63,-59.35,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assay				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128325 BindingDB Entry DOI: 10.7270/Q2KD22N4
					More data for this Ligand-Target Pair