null

SMILES: CCCCc1nc(=O)c(c(O)n1-c1c(OC)cccc1OC)S(=O)(=O)c1ccc(cc1)C1CC1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50567168   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apelin receptor (Homo sapiens (Human))	BDBM50567168 (CHEMBL4864542) Show SMILES CCCCc1nc(=O)c(c(O)n1-c1c(OC)cccc1OC)S(=O)(=O)c1ccc(cc1)C1CC1 |(40.9,-21.23,;42.23,-22,;43.57,-21.24,;44.9,-22,;46.23,-21.24,;46.24,-19.69,;47.56,-18.92,;47.56,-17.38,;48.9,-19.69,;48.91,-21.24,;50.24,-22,;47.57,-22.01,;47.57,-23.54,;48.9,-24.31,;50.23,-23.54,;51.57,-24.3,;48.91,-25.85,;47.57,-26.62,;46.23,-25.85,;46.23,-24.31,;44.9,-23.54,;43.57,-24.31,;50.23,-18.91,;49.45,-17.57,;51,-17.57,;51.57,-19.68,;51.57,-21.21,;52.9,-21.98,;54.23,-21.2,;54.22,-19.65,;52.89,-18.9,;55.57,-21.96,;56.35,-23.29,;57.11,-21.96,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0200	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assay				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128325 BindingDB Entry DOI: 10.7270/Q2KD22N4
					More data for this Ligand-Target Pair
Apelin receptor (Mus musculus)	BDBM50567168 (CHEMBL4864542) Show SMILES CCCCc1nc(=O)c(c(O)n1-c1c(OC)cccc1OC)S(=O)(=O)c1ccc(cc1)C1CC1 |(40.9,-21.23,;42.23,-22,;43.57,-21.24,;44.9,-22,;46.23,-21.24,;46.24,-19.69,;47.56,-18.92,;47.56,-17.38,;48.9,-19.69,;48.91,-21.24,;50.24,-22,;47.57,-22.01,;47.57,-23.54,;48.9,-24.31,;50.23,-23.54,;51.57,-24.3,;48.91,-25.85,;47.57,-26.62,;46.23,-25.85,;46.23,-24.31,;44.9,-23.54,;43.57,-24.31,;50.23,-18.91,;49.45,-17.57,;51,-17.57,;51.57,-19.68,;51.57,-21.21,;52.9,-21.98,;54.23,-21.2,;54.22,-19.65,;52.89,-18.9,;55.57,-21.96,;56.35,-23.29,;57.11,-21.96,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at mouse APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assay				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128325 BindingDB Entry DOI: 10.7270/Q2KD22N4
					More data for this Ligand-Target Pair
Apelin receptor (Rattus norvegicus)	BDBM50567168 (CHEMBL4864542) Show SMILES CCCCc1nc(=O)c(c(O)n1-c1c(OC)cccc1OC)S(=O)(=O)c1ccc(cc1)C1CC1 |(40.9,-21.23,;42.23,-22,;43.57,-21.24,;44.9,-22,;46.23,-21.24,;46.24,-19.69,;47.56,-18.92,;47.56,-17.38,;48.9,-19.69,;48.91,-21.24,;50.24,-22,;47.57,-22.01,;47.57,-23.54,;48.9,-24.31,;50.23,-23.54,;51.57,-24.3,;48.91,-25.85,;47.57,-26.62,;46.23,-25.85,;46.23,-24.31,;44.9,-23.54,;43.57,-24.31,;50.23,-18.91,;49.45,-17.57,;51,-17.57,;51.57,-19.68,;51.57,-21.21,;52.9,-21.98,;54.23,-21.2,;54.22,-19.65,;52.89,-18.9,;55.57,-21.96,;56.35,-23.29,;57.11,-21.96,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0600	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assay				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128325 BindingDB Entry DOI: 10.7270/Q2KD22N4
					More data for this Ligand-Target Pair