BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

null

SMILES: COc1ccc(CNC2CC22CCc3ccccc23)cc1OC

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50568529
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50568529 (CHEMBL4851339) Show SMILES COc1ccc(CNC2CC22CCc3ccccc23)cc1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human LSD1 (172 to 852 residues) using Bio-H3K4me2 (1 to 24 residues) as substrate incubated for 1 hr by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB
TBA					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50568529 (CHEMBL4851339) Show SMILES COc1ccc(CNC2CC22CCc3ccccc23)cc1OC Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAO-B expressed in baculovirus infected BTI insect cells by fluorescence method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB
TBA					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM50568529 (CHEMBL4851339) Show SMILES COc1ccc(CNC2CC22CCc3ccccc23)cc1OC Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAO-A expressed in baculovirus infected BTI insect cells by fluorescence method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00919 BindingDB Entry DOI: 10.7270/Q28K7DTB
TBA					More data for this Ligand-Target Pair