Search and Browse
Download
Enter Data
null
SMILES: CCN(CCCCOc1ccc(C(=O)\C=C\c2ccc(cc2)N(C)C)c(O)c1)Cc1ccccc1N(C)C
InChI Key:
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM50569012 (CHEMBL4865817) | UniProtKB/SwissProt GoogleScholar AffyNet  | PC cid PC sid UniChem | Article PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Mixed type inhibition of electric eel AChE by reciprocal Lineweaver-Burk plot analysis | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113310 BindingDB Entry DOI: 10.7270/Q28G8QGX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Rattus norvegicus (rat)) | BDBM50569012 (CHEMBL4865817) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat cortex homogenate acetylcholinesterase by Ellman's method | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113310 BindingDB Entry DOI: 10.7270/Q28G8QGX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carboxylic ester hydrolase (Rattus norvegicus (rat)) | BDBM50569012 (CHEMBL4865817) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.36E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat serum BuChE by Ellman's method | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113310 BindingDB Entry DOI: 10.7270/Q28G8QGX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM50569012 (CHEMBL4865817) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant MAO-A by multimode plate reader assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113310 BindingDB Entry DOI: 10.7270/Q28G8QGX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50569012 (CHEMBL4865817) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant MAO-B by multimode plate reader assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113310 BindingDB Entry DOI: 10.7270/Q28G8QGX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amyloid-beta precursor protein (Homo sapiens (Human)) | BDBM50569012 (CHEMBL4865817) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of self-induced amyloid beta (1 to 42) (unknown origin) aggregation by T-fluorescence assay relative to control | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113310 BindingDB Entry DOI: 10.7270/Q28G8QGX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM50569012 (CHEMBL4865817) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's method | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113310 BindingDB Entry DOI: 10.7270/Q28G8QGX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
