Found 2 hits for monomerid = 50569296 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50569296
(CHEMBL4852629)Show SMILES O[C@@H](CNCCCCCCCCOc1cccc(c1)C(NC(=O)O[C@H]1CN2CCC1CC2)c1ccccc1)c1ccc(O)c2[nH]c(=O)ccc12 |r,wU:1.0,24.24,(3.65,-24.81,;4.98,-25.58,;6.32,-24.81,;7.65,-25.57,;8.98,-24.8,;10.32,-25.56,;11.65,-24.79,;12.99,-25.56,;14.32,-24.78,;15.65,-25.55,;16.99,-24.77,;18.32,-25.54,;19.65,-24.77,;20.99,-25.42,;20.98,-26.95,;22.32,-27.72,;23.65,-26.94,;23.64,-25.4,;22.31,-24.64,;24.98,-24.61,;26.31,-25.37,;27.64,-24.6,;27.63,-23.06,;28.98,-25.36,;30.31,-24.58,;30.3,-23.05,;31.63,-22.28,;32.97,-23.05,;32.97,-24.59,;31.65,-25.36,;32.34,-24,;30.85,-23.61,;24.97,-23.08,;26.3,-22.31,;26.29,-20.77,;24.95,-20,;23.62,-20.79,;23.63,-22.32,;4.99,-27.12,;3.66,-27.89,;3.66,-29.44,;4.99,-30.21,;5,-31.75,;6.32,-29.43,;7.65,-30.2,;9,-29.43,;10.33,-30.21,;9,-27.89,;7.66,-27.11,;6.32,-27.88,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of 125I-cyanopindolol from human adrenergic beta2 receptor |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127975 BindingDB Entry DOI: 10.7270/Q2F193HC |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50569296
(CHEMBL4852629)Show SMILES O[C@@H](CNCCCCCCCCOc1cccc(c1)C(NC(=O)O[C@H]1CN2CCC1CC2)c1ccccc1)c1ccc(O)c2[nH]c(=O)ccc12 |r,wU:1.0,24.24,(3.65,-24.81,;4.98,-25.58,;6.32,-24.81,;7.65,-25.57,;8.98,-24.8,;10.32,-25.56,;11.65,-24.79,;12.99,-25.56,;14.32,-24.78,;15.65,-25.55,;16.99,-24.77,;18.32,-25.54,;19.65,-24.77,;20.99,-25.42,;20.98,-26.95,;22.32,-27.72,;23.65,-26.94,;23.64,-25.4,;22.31,-24.64,;24.98,-24.61,;26.31,-25.37,;27.64,-24.6,;27.63,-23.06,;28.98,-25.36,;30.31,-24.58,;30.3,-23.05,;31.63,-22.28,;32.97,-23.05,;32.97,-24.59,;31.65,-25.36,;32.34,-24,;30.85,-23.61,;24.97,-23.08,;26.3,-22.31,;26.29,-20.77,;24.95,-20,;23.62,-20.79,;23.63,-22.32,;4.99,-27.12,;3.66,-27.89,;3.66,-29.44,;4.99,-30.21,;5,-31.75,;6.32,-29.43,;7.65,-30.2,;9,-29.43,;10.33,-30.21,;9,-27.89,;7.66,-27.11,;6.32,-27.88,)| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of [3H]-N-methylscopolamine from human muscarinic M3 receptor |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127975 BindingDB Entry DOI: 10.7270/Q2F193HC |
More data for this Ligand-Target Pair | |