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SMILES: CN1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50569852   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mucolipin-1


(Homo sapiens)
BDBM50569852
PNG
(CHEMBL4856325)
Show SMILES CN1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.33E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mi...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-3


(Homo sapiens (Human))
BDBM50569852
PNG
(CHEMBL4856325)
Show SMILES CN1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair
Mucolipin-2


(Homo sapiens)
BDBM50569852
PNG
(CHEMBL4856325)
Show SMILES CN1CCN(CC1)[C@H]1CCCC[C@@H]1NS(=O)(=O)c1ccccc1 |r|
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.02E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human TRPML2-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by F...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112966
BindingDB Entry DOI: 10.7270/Q2862M7H
More data for this
Ligand-Target Pair