null

SMILES: CCCCc1[nH]c(=O)c(-c2nnc(Cc3ccc(Cl)cc3)o2)c(O)c1-c1c(OC)cccc1OC

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570420   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apelin receptor (Rattus norvegicus)	BDBM50570420 (CHEMBL4861053) Show SMILES CCCCc1[nH]c(=O)c(-c2nnc(Cc3ccc(Cl)cc3)o2)c(O)c1-c1c(OC)cccc1OC |(36.73,-14.63,;38.06,-15.39,;39.39,-14.61,;40.73,-15.37,;42.06,-14.6,;42.05,-13.06,;43.39,-12.28,;43.38,-10.74,;44.72,-13.05,;46.05,-12.27,;46.21,-10.74,;47.71,-10.42,;48.49,-11.75,;50.02,-11.9,;50.65,-13.31,;49.74,-14.55,;50.37,-15.96,;51.9,-16.12,;52.53,-17.53,;52.81,-14.86,;52.17,-13.46,;47.46,-12.89,;44.73,-14.58,;46.06,-15.36,;43.39,-15.36,;43.4,-16.89,;42.07,-17.66,;40.74,-16.9,;39.41,-17.67,;42.07,-19.21,;43.41,-19.98,;44.74,-19.21,;44.74,-17.66,;46.07,-16.88,;47.4,-17.65,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat APJ receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 1 hr...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01878 BindingDB Entry DOI: 10.7270/Q20G3PXZ
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50570420 (CHEMBL4861053) Show SMILES CCCCc1[nH]c(=O)c(-c2nnc(Cc3ccc(Cl)cc3)o2)c(O)c1-c1c(OC)cccc1OC |(36.73,-14.63,;38.06,-15.39,;39.39,-14.61,;40.73,-15.37,;42.06,-14.6,;42.05,-13.06,;43.39,-12.28,;43.38,-10.74,;44.72,-13.05,;46.05,-12.27,;46.21,-10.74,;47.71,-10.42,;48.49,-11.75,;50.02,-11.9,;50.65,-13.31,;49.74,-14.55,;50.37,-15.96,;51.9,-16.12,;52.53,-17.53,;52.81,-14.86,;52.17,-13.46,;47.46,-12.89,;44.73,-14.58,;46.06,-15.36,;43.39,-15.36,;43.4,-16.89,;42.07,-17.66,;40.74,-16.9,;39.41,-17.67,;42.07,-19.21,;43.41,-19.98,;44.74,-19.21,;44.74,-17.66,;46.07,-16.88,;47.4,-17.65,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human APJ receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01878 BindingDB Entry DOI: 10.7270/Q20G3PXZ
					More data for this Ligand-Target Pair