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SMILES: Cc1ccc(cc1)-c1csc(NC(=O)CN2CCN(CC2)c2cc(=O)[nH]c3ccc(F)cc23)n1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50571068   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50571068
PNG
(CHEMBL4866817)
Show SMILES Cc1ccc(cc1)-c1csc(NC(=O)CN2CCN(CC2)c2cc(=O)[nH]c3ccc(F)cc23)n1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 296n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of VEGFR-2 (unknown origin) by using poly (Glu:Tyr 4:1) as substrate measured after 45 mins by Kinase-Glo max based microplate reader

Citation and Details

Article DOI: 10.1016/j.bmc.2021.116168
BindingDB Entry DOI: 10.7270/Q25X2DQM
More data for this
Ligand-Target Pair