null
SMILES: COc1ccc(cc1)-c1csc(NC(=O)CN2CCN(CC2)c2cc(=O)[nH]c3ccc(F)cc23)n1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50571069 (CHEMBL4853870) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of VEGFR-2 (unknown origin) by using poly (Glu:Tyr 4:1) as substrate measured after 45 mins by Kinase-Glo max based microplate reader | Citation and Details Article DOI: 10.1016/j.bmc.2021.116168 BindingDB Entry DOI: 10.7270/Q25X2DQM | |||||||||||
More data for this Ligand-Target Pair |