null
SMILES: OC1(CSC(=S)N1Cc1ccncc1)c1ccccc1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM50571206 (CHEMBL4861930) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human GSK-3beta incubated with substrate in presence of ATP measured by serial dilution assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116179 BindingDB Entry DOI: 10.7270/Q2H70KMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM50571206 (CHEMBL4861930) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.21E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human GSK-3beta C199A mutant incubated with substrate in presence of ATP measured by serial dilution assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116179 BindingDB Entry DOI: 10.7270/Q2H70KMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 alpha (Homo sapiens (Human)) | BDBM50571206 (CHEMBL4861930) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human wild type GSK-3beta incubated with substrate in presence of ATP measured by serial dilution assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116179 BindingDB Entry DOI: 10.7270/Q2H70KMS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM50571206 (CHEMBL4861930) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 102 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human GSK-3beta preincubated for 3 hrs followed by ATP and substrate addition measured by serial dilution assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116179 BindingDB Entry DOI: 10.7270/Q2H70KMS | |||||||||||
More data for this Ligand-Target Pair |