null

SMILES: Cl.COc1cccc(OC)c1-c1cc(nn1C1CCCC1)C(=O)N[C@@H](CCN1CCCCC1)CC(O)=O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50571378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apelin receptor (Homo sapiens (Human))	BDBM50571378 (CHEMBL4852570) Show SMILES Cl.COc1cccc(OC)c1-c1cc(nn1C1CCCC1)C(=O)N[C@@H](CCN1CCCCC1)CC(O)=O |r,wU:24.26,(57.58,-16.5,;46.68,-13.06,;47.83,-14.09,;47.51,-15.59,;46.05,-16.07,;45.73,-17.58,;46.88,-18.61,;48.34,-18.13,;49.49,-19.15,;49.18,-20.66,;48.65,-16.63,;50.11,-16.15,;50.58,-14.68,;52.12,-14.68,;52.6,-16.15,;51.36,-17.05,;51.36,-18.59,;50.12,-19.5,;50.59,-20.96,;52.13,-20.96,;52.61,-19.5,;53.03,-13.43,;52.4,-12.03,;54.56,-13.59,;55.46,-12.35,;54.83,-10.94,;55.74,-9.69,;55.11,-8.29,;56.02,-7.04,;55.4,-5.64,;53.87,-5.47,;52.96,-6.72,;53.58,-8.13,;56.99,-12.5,;57.9,-11.26,;59.43,-11.42,;57.27,-9.85,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.57E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human AGTRL1 expressed in CHO-K1 cells assessed as induction of beta-arrestin 2 recruitment incubated for 90 mins by PathHunter a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01448 BindingDB Entry DOI: 10.7270/Q2TH8RGN
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50571378 (CHEMBL4852570) Show SMILES Cl.COc1cccc(OC)c1-c1cc(nn1C1CCCC1)C(=O)N[C@@H](CCN1CCCCC1)CC(O)=O |r,wU:24.26,(57.58,-16.5,;46.68,-13.06,;47.83,-14.09,;47.51,-15.59,;46.05,-16.07,;45.73,-17.58,;46.88,-18.61,;48.34,-18.13,;49.49,-19.15,;49.18,-20.66,;48.65,-16.63,;50.11,-16.15,;50.58,-14.68,;52.12,-14.68,;52.6,-16.15,;51.36,-17.05,;51.36,-18.59,;50.12,-19.5,;50.59,-20.96,;52.13,-20.96,;52.61,-19.5,;53.03,-13.43,;52.4,-12.03,;54.56,-13.59,;55.46,-12.35,;54.83,-10.94,;55.74,-9.69,;55.11,-8.29,;56.02,-7.04,;55.4,-5.64,;53.87,-5.47,;52.96,-6.72,;53.58,-8.13,;56.99,-12.5,;57.9,-11.26,;59.43,-11.42,;57.27,-9.85,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human APJ receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 40 mins by...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01448 BindingDB Entry DOI: 10.7270/Q2TH8RGN
					More data for this Ligand-Target Pair