null

SMILES: COc1cccc(OC)c1-c1cc(nn1C1CCCC1)C(=O)N[C@@H](CCN1CCCCC1)CC(=O)Nc1nccs1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50571401   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apelin receptor (Homo sapiens (Human))	BDBM50571401 (CHEMBL4867710) Show SMILES COc1cccc(OC)c1-c1cc(nn1C1CCCC1)C(=O)N[C@@H](CCN1CCCCC1)CC(=O)Nc1nccs1 |r,wU:23.26,(62.77,-29.2,;63.91,-30.23,;63.59,-31.73,;62.13,-32.21,;61.81,-33.72,;62.97,-34.75,;64.43,-34.27,;65.57,-35.29,;65.26,-36.8,;64.74,-32.77,;66.19,-32.29,;66.67,-30.82,;68.21,-30.82,;68.69,-32.28,;67.44,-33.19,;67.45,-34.73,;66.21,-35.64,;66.68,-37.1,;68.22,-37.1,;68.7,-35.64,;69.11,-29.57,;68.48,-28.17,;70.64,-29.73,;71.55,-28.48,;70.92,-27.08,;71.82,-25.83,;71.19,-24.43,;72.1,-23.18,;71.48,-21.77,;69.95,-21.61,;69.04,-22.85,;69.67,-24.27,;73.08,-28.64,;73.98,-27.4,;73.35,-25.99,;75.51,-27.55,;76.42,-26.31,;77.95,-26.3,;78.42,-24.84,;77.17,-23.93,;75.93,-24.84,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human AGTRL1 expressed in CHO-K1 cells assessed as induction of beta-arrestin 2 recruitment incubated for 90 mins by PathHunter a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01448 BindingDB Entry DOI: 10.7270/Q2TH8RGN
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50571401 (CHEMBL4867710) Show SMILES COc1cccc(OC)c1-c1cc(nn1C1CCCC1)C(=O)N[C@@H](CCN1CCCCC1)CC(=O)Nc1nccs1 |r,wU:23.26,(62.77,-29.2,;63.91,-30.23,;63.59,-31.73,;62.13,-32.21,;61.81,-33.72,;62.97,-34.75,;64.43,-34.27,;65.57,-35.29,;65.26,-36.8,;64.74,-32.77,;66.19,-32.29,;66.67,-30.82,;68.21,-30.82,;68.69,-32.28,;67.44,-33.19,;67.45,-34.73,;66.21,-35.64,;66.68,-37.1,;68.22,-37.1,;68.7,-35.64,;69.11,-29.57,;68.48,-28.17,;70.64,-29.73,;71.55,-28.48,;70.92,-27.08,;71.82,-25.83,;71.19,-24.43,;72.1,-23.18,;71.48,-21.77,;69.95,-21.61,;69.04,-22.85,;69.67,-24.27,;73.08,-28.64,;73.98,-27.4,;73.35,-25.99,;75.51,-27.55,;76.42,-26.31,;77.95,-26.3,;78.42,-24.84,;77.17,-23.93,;75.93,-24.84,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human APJ receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 40 mins by...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01448 BindingDB Entry DOI: 10.7270/Q2TH8RGN
					More data for this Ligand-Target Pair