null

SMILES: COc1cccc(OC)c1-c1cc(nn1C1CCCC1)C(=O)N[C@@H](CCN1CCCCC1)Cc1nnc[nH]1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50571406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apelin receptor (Homo sapiens (Human))	BDBM50571406 (CHEMBL4876051) Show SMILES COc1cccc(OC)c1-c1cc(nn1C1CCCC1)C(=O)N[C@@H](CCN1CCCCC1)Cc1nnc[nH]1 |r,wU:23.26,(2.18,-9.73,;3.32,-10.76,;3,-12.27,;1.54,-12.74,;1.22,-14.25,;2.38,-15.28,;3.84,-14.8,;4.99,-15.82,;4.67,-17.33,;4.15,-13.3,;5.61,-12.82,;6.08,-11.35,;7.62,-11.35,;8.1,-12.82,;6.85,-13.72,;6.86,-15.26,;5.62,-16.17,;6.09,-17.63,;7.63,-17.63,;8.11,-16.17,;8.52,-10.11,;7.89,-8.7,;10.05,-10.26,;10.96,-9.02,;10.33,-7.61,;11.23,-6.36,;10.6,-4.96,;11.52,-3.71,;10.89,-2.31,;9.36,-2.14,;8.45,-3.39,;9.08,-4.8,;12.49,-9.18,;13.39,-7.93,;12.89,-6.48,;14.13,-5.57,;15.38,-6.46,;14.91,-7.93,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	523	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human AGTRL1 expressed in CHO-K1 cells assessed as induction of beta-arrestin 2 recruitment incubated for 90 mins by PathHunter a...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01448 BindingDB Entry DOI: 10.7270/Q2TH8RGN
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50571406 (CHEMBL4876051) Show SMILES COc1cccc(OC)c1-c1cc(nn1C1CCCC1)C(=O)N[C@@H](CCN1CCCCC1)Cc1nnc[nH]1 |r,wU:23.26,(2.18,-9.73,;3.32,-10.76,;3,-12.27,;1.54,-12.74,;1.22,-14.25,;2.38,-15.28,;3.84,-14.8,;4.99,-15.82,;4.67,-17.33,;4.15,-13.3,;5.61,-12.82,;6.08,-11.35,;7.62,-11.35,;8.1,-12.82,;6.85,-13.72,;6.86,-15.26,;5.62,-16.17,;6.09,-17.63,;7.63,-17.63,;8.11,-16.17,;8.52,-10.11,;7.89,-8.7,;10.05,-10.26,;10.96,-9.02,;10.33,-7.61,;11.23,-6.36,;10.6,-4.96,;11.52,-3.71,;10.89,-2.31,;9.36,-2.14,;8.45,-3.39,;9.08,-4.8,;12.49,-9.18,;13.39,-7.93,;12.89,-6.48,;14.13,-5.57,;15.38,-6.46,;14.91,-7.93,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	134	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human APJ receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 40 mins by...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01448 BindingDB Entry DOI: 10.7270/Q2TH8RGN
					More data for this Ligand-Target Pair