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SMILES: CCNCCC(=O)Nc1c[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C

InChI Key:

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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50571488   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))		BDBM50571488
PNG
(CHEMBL4862737)
Show SMILES CCNCCC(=O)Nc1c[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of FLT3 (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02247
BindingDB Entry DOI: 10.7270/Q29G5RKV
More data for this
Ligand-Target Pair