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null

SMILES: COc1ccc(CCc2nc3cc(ccn3c2NC2CCCCC2)-c2c(C)noc2C)cc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50571550
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
CREB-binding protein (Homo sapiens (Human))	BDBM50571550 (CHEMBL4867046) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	159	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of His-tagged CBP (unknown origin) using biotinylated-H3K56ac peptide as substrate incubated for 1 hr by AlphaScreen assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02232 BindingDB Entry DOI: 10.7270/Q2NS0ZQF
TBA					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50571550 (CHEMBL4867046) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of His-tagged BRD4 BD1 (unknown origin) using biotinylated-JQ1 peptide as substrate incubated for 1 hr by AlphaScreen assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02232 BindingDB Entry DOI: 10.7270/Q2NS0ZQF
TBA					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50571550 (CHEMBL4867046) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human partial length BRD4 bromodomain 1 long isoform (N44 to E168 residues) expressed in bacterial expression system by BromoELEC...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02232 BindingDB Entry DOI: 10.7270/Q2NS0ZQF
TBA					More data for this Ligand-Target Pair
Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50571550 (CHEMBL4867046) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	285	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human partial length EP300 (A1040 to G1161 residues) expressed in bacterial expression system by BromoELECT assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02232 BindingDB Entry DOI: 10.7270/Q2NS0ZQF
TBA					More data for this Ligand-Target Pair
CREB-binding protein (Homo sapiens (Human))	BDBM50571550 (CHEMBL4867046) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	265	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human partial length CREBBP (R1081 to G1197 residues) expressed in bacterial expression system by BromoELECT assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02232 BindingDB Entry DOI: 10.7270/Q2NS0ZQF
TBA					More data for this Ligand-Target Pair