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SMILES: CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50571706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
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Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
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Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
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NT-3 growth factor receptor (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
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BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM50571706 (CHEMBL4850588) Show SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3ccccc3Cl)n2)C(F)(F)F)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	103	n/a	n/a	n/a	n/a	n/a	n/a
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