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SMILES: OC(=O)c1ccc(cc1C1CCCC1)-c1ccnc2[nH]c(nc12)-c1ccccc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50572893   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium/calmodulin-dependent protein kinase kinase 2 (Homo sapiens (Human))	BDBM50572893 (CHEMBL4870467) Show SMILES OC(=O)c1ccc(cc1C1CCCC1)-c1ccnc2[nH]c(nc12)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to control				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02274 BindingDB Entry DOI: 10.7270/Q2MG7T9N
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase kinase 2 (Homo sapiens (Human))	BDBM50572893 (CHEMBL4870467) Show SMILES OC(=O)c1ccc(cc1C1CCCC1)-c1ccnc2[nH]c(nc12)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CAMKK2 in human LNCaP C4-2 cells assessed as reduction AMPK phosphorylation at Thr172 incubated for 24 hrs by Western blot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02274 BindingDB Entry DOI: 10.7270/Q2MG7T9N
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase kinase 1 (Homo sapiens (Human))	BDBM50572893 (CHEMBL4870467) Show SMILES OC(=O)c1ccc(cc1C1CCCC1)-c1ccnc2[nH]c(nc12)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CAMKK1 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to control				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02274 BindingDB Entry DOI: 10.7270/Q2MG7T9N
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase kinase 2 (Homo sapiens (Human))	BDBM50572893 (CHEMBL4870467) Show SMILES OC(=O)c1ccc(cc1C1CCCC1)-c1ccnc2[nH]c(nc12)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NanoLuc-fused CAMKK2 (unknown origin) expressed in HEK293 cells after 24 hrs by NanoBRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02274 BindingDB Entry DOI: 10.7270/Q2MG7T9N
					More data for this Ligand-Target Pair