null
SMILES: CN(C)CCCNc1ccc(cc1[N+]([O-])=O)S(=O)(=O)NC(=O)c1ccc(cc1Oc1cnc2[nH]ccc2c1)N1CCN(CC2=C(CC(C)(C)CC2)c2ccc(cc2)C(F)(F)F)CC1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM50573269![]() (CHEMBL4860213) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of Bak derived peptide from Bcl-xL (unknown origin) measured after 15 mins by microplate reader assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116350 BindingDB Entry DOI: 10.7270/Q2R2155T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM50573269![]() (CHEMBL4860213) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.890 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of Bak derived peptide from Bcl-2 (unknown origin) measured after 15 mins by microplate reader assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116350 BindingDB Entry DOI: 10.7270/Q2R2155T | |||||||||||
More data for this Ligand-Target Pair |