null
SMILES: CC1(C)CCC(CN2CCN(CC2)c2ccc(C(=O)NS(=O)(=O)c3ccc(NC4CCOC4)c(c3)[N+]([O-])=O)c(Oc3cnc4[nH]ccc4c3)c2)=C(C1)c1ccc(cc1)C(F)(F)F
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM50573274 (CHEMBL4860155) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 837 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of Bak derived peptide from Bcl-xL (unknown origin) measured after 15 mins by microplate reader assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116350 BindingDB Entry DOI: 10.7270/Q2R2155T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM50573274 (CHEMBL4860155) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of Bak derived peptide from Bcl-2 (unknown origin) measured after 15 mins by microplate reader assay | Citation and Details Article DOI: 10.1016/j.bmc.2021.116350 BindingDB Entry DOI: 10.7270/Q2R2155T | |||||||||||
More data for this Ligand-Target Pair |