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null

SMILES: O=S(=O)(c1ccccc1)n1ccc2c(OCCNCC3CCCCC3)cccc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50574185
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50574185 (CHEMBL4854460) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in CHO-K1 membrane incubated for 60 mins by solid scintillation counting analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113792 BindingDB Entry DOI: 10.7270/Q2514325
TBA					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM50574185 (CHEMBL4854460) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	551	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BuChE in human plasma using BTC as substrate preincubated with enzyme for 5 mins followed by substrate addition for 5 mins by Ellman's ...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113792 BindingDB Entry DOI: 10.7270/Q2514325
TBA					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50574185 (CHEMBL4854460) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of equine serum BuChE using BTC as substrate preincubated with enzyme for 5 mins followed by substrate addition for 5 mins by Ellman's met...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113792 BindingDB Entry DOI: 10.7270/Q2514325
TBA					More data for this Ligand-Target Pair