null
SMILES: C\C(C\C=C/C(C)(C)O)=C/CC[C@@]1(C)Oc2cc(C)c(C(O)=O)c(O)c2C=C1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50575002![]() (CHEMBL4859368) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.81E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant PTP1B (1 to 322 residues) expressed in Escherichia coli using pNPP as substrate preincubated with substrate for 10 mi... | Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00454 BindingDB Entry DOI: 10.7270/Q2BC43C6 | |||||||||||
More data for this Ligand-Target Pair |