null
SMILES: Cc1ccc(cc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1)-c1n[nH]c(=O)o1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Interleukin-2 (Homo sapiens (Human)) | BDBM50575330 (CHEMBL4872805) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 227 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01403 BindingDB Entry DOI: 10.7270/Q2C82F4Q | |||||||||||
More data for this Ligand-Target Pair |