null
SMILES: CC(C)CS(=O)(=O)Nc1ccc(nn1)-c1ccc(F)cc1N1CCCCC1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kynurenine 3-monooxygenase (Homo sapiens (Human)) | BDBM50576350 (CHEMBL4877327) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min... | Citation and Details Article DOI: 10.1016/j.bmcl.2021.128115 BindingDB Entry DOI: 10.7270/Q2XW4PN8 | |||||||||||
More data for this Ligand-Target Pair |