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SMILES: COc1cc(OC)cc(c1)N(CCNC1CCC(O)CC1)c1ccc2ncc(-c3cnn(C)c3)c(=O)n2c1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50577015   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50577015
PNG
(CHEMBL4851029)
Show SMILES COc1cc(OC)cc(c1)N(CCNC1CCC(O)CC1)c1ccc2ncc(-c3cnn(C)c3)c(=O)n2c1 |(74.36,-53.02,;73.03,-53.8,;71.69,-53.03,;71.68,-51.48,;70.33,-50.72,;70.32,-49.18,;71.65,-48.39,;69,-51.5,;69.01,-53.03,;70.35,-53.81,;67.68,-53.81,;67.68,-55.36,;66.35,-56.13,;66.35,-57.67,;65.02,-58.44,;63.69,-57.67,;62.37,-58.44,;62.36,-59.97,;61.03,-60.74,;63.69,-60.75,;65.03,-59.98,;66.33,-53.04,;66.33,-51.49,;64.99,-50.73,;63.66,-51.5,;62.32,-50.74,;60.99,-51.51,;60.98,-53.06,;59.66,-53.83,;59.49,-55.36,;57.99,-55.67,;57.22,-54.34,;55.69,-54.19,;58.25,-53.2,;62.32,-53.83,;62.33,-55.38,;63.66,-53.05,;65,-53.82,)|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human N-terminal GST fusion tagged FGFR1 cytoplasmic domain (398 to 822 residues) expressed in baculovirus infected Sf21 insect cells i...

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113499
BindingDB Entry DOI: 10.7270/Q2HH6PWN
More data for this
Ligand-Target Pair