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SMILES: OC(=O)c1ccc(Cn2c(NC3CCN(CCc4ccc(cc4)C#N)CC3)nc3ccccc23)cc1

InChI Key:

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50577257   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))		BDBM50577257
PNG
(CHEMBL4856218)
Show SMILES OC(=O)c1ccc(Cn2c(NC3CCN(CCc4ccc(cc4)C#N)CC3)nc3ccccc23)cc1
PDB
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PC cid
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n/an/a 4.16E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human ERG stably expressed in CHO-K1 cells at -90 mV holding potential by automated Q-patch clamp method

Citation and Details

Article DOI: 10.1021/acsmedchemlett.1c00328
BindingDB Entry DOI: 10.7270/Q2639TJ1
More data for this
Ligand-Target Pair