null

SMILES: CCCCc1nc(=O)c(C(=O)N2CC[C@H](C2)c2ccccc2)c(O)n1-c1c(OC)cccc1OC

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50577747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apelin receptor (Rattus norvegicus)	BDBM50577747 (CHEMBL4872407) Show SMILES CCCCc1nc(=O)c(C(=O)N2CC[C@H](C2)c2ccccc2)c(O)n1-c1c(OC)cccc1OC |r,wD:14.16,(25.17,-48.11,;26.5,-48.88,;27.83,-48.11,;29.17,-48.87,;30.52,-48.11,;30.52,-46.57,;31.84,-45.8,;31.84,-44.24,;33.17,-46.57,;34.51,-45.79,;34.51,-44.25,;35.84,-46.56,;36,-48.08,;37.51,-48.4,;38.28,-47.07,;37.25,-45.92,;39.81,-46.91,;40.71,-48.16,;42.24,-48,;42.86,-46.59,;41.95,-45.34,;40.42,-45.51,;33.17,-48.09,;34.51,-48.86,;31.85,-48.85,;31.85,-50.39,;33.18,-51.15,;34.51,-50.38,;35.85,-51.14,;33.19,-52.7,;31.85,-53.48,;30.51,-52.71,;30.52,-51.16,;29.18,-50.39,;27.85,-51.16,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.340	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat APJ receptor expressed in HEK293T cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production in...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00385 BindingDB Entry DOI: 10.7270/Q2M330MF
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM50577747 (CHEMBL4872407) Show SMILES CCCCc1nc(=O)c(C(=O)N2CC[C@H](C2)c2ccccc2)c(O)n1-c1c(OC)cccc1OC |r,wD:14.16,(25.17,-48.11,;26.5,-48.88,;27.83,-48.11,;29.17,-48.87,;30.52,-48.11,;30.52,-46.57,;31.84,-45.8,;31.84,-44.24,;33.17,-46.57,;34.51,-45.79,;34.51,-44.25,;35.84,-46.56,;36,-48.08,;37.51,-48.4,;38.28,-47.07,;37.25,-45.92,;39.81,-46.91,;40.71,-48.16,;42.24,-48,;42.86,-46.59,;41.95,-45.34,;40.42,-45.51,;33.17,-48.09,;34.51,-48.86,;31.85,-48.85,;31.85,-50.39,;33.18,-51.15,;34.51,-50.38,;35.85,-51.14,;33.19,-52.7,;31.85,-53.48,;30.51,-52.71,;30.52,-51.16,;29.18,-50.39,;27.85,-51.16,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.260	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human APJ receptor expressed in HEK293T cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00385 BindingDB Entry DOI: 10.7270/Q2M330MF
					More data for this Ligand-Target Pair