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SMILES: CCOc1ccc(nc1)-c1nnc(n1-c1ccccn1)C12CC(C1)(C2)NC(=O)c1ccnc2cccnc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50579968   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM50579968 (CHEMBL5072404 | US11926614, Example 122) Show SMILES CCOc1ccc(nc1)-c1nnc(n1-c1ccccn1)C12CC(C1)(C2)NC(=O)c1ccnc2cccnc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM50579968 (CHEMBL5072404 | US11926614, Example 122) Show SMILES CCOc1ccc(nc1)-c1nnc(n1-c1ccccn1)C12CC(C1)(C2)NC(=O)c1ccnc2cccnc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NAD				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01264 BindingDB Entry DOI: 10.7270/Q21R6VDH
					More data for this Ligand-Target Pair