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SMILES: Cc1cccc(n1)-c1nnc([C@H]2C[C@@H](C2)NC(=O)c2cc(F)cc3nccnc23)n1-c1ccccc1F

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50579984   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM50579984 (CHEMBL5093991 | US11926614, Example 202) Show SMILES Cc1cccc(n1)-c1nnc([C@H]2C[C@@H](C2)NC(=O)c2cc(F)cc3nccnc23)n1-c1ccccc1F |r,wU:13.16,wD:11.11,(39.73,-24.55,;41.25,-24.71,;41.87,-26.11,;43.39,-26.26,;44.28,-25.03,;43.66,-23.65,;42.15,-23.48,;44.56,-22.42,;44.09,-20.95,;45.33,-20.03,;46.59,-20.95,;48.06,-20.46,;49.43,-21.17,;50.14,-19.8,;48.76,-19.09,;51.61,-19.32,;51.94,-17.81,;50.78,-16.77,;53.41,-17.32,;53.72,-15.81,;55.19,-15.33,;55.5,-13.84,;56.35,-16.36,;56.03,-17.88,;57.17,-18.9,;56.85,-20.41,;55.38,-20.89,;54.23,-19.86,;54.56,-18.35,;46.11,-22.42,;47.01,-23.65,;46.38,-25.04,;47.27,-26.28,;48.79,-26.12,;49.41,-24.71,;48.51,-23.49,;49.12,-22.09,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM50579984 (CHEMBL5093991 | US11926614, Example 202) Show SMILES Cc1cccc(n1)-c1nnc([C@H]2C[C@@H](C2)NC(=O)c2cc(F)cc3nccnc23)n1-c1ccccc1F |r,wU:13.16,wD:11.11,(39.73,-24.55,;41.25,-24.71,;41.87,-26.11,;43.39,-26.26,;44.28,-25.03,;43.66,-23.65,;42.15,-23.48,;44.56,-22.42,;44.09,-20.95,;45.33,-20.03,;46.59,-20.95,;48.06,-20.46,;49.43,-21.17,;50.14,-19.8,;48.76,-19.09,;51.61,-19.32,;51.94,-17.81,;50.78,-16.77,;53.41,-17.32,;53.72,-15.81,;55.19,-15.33,;55.5,-13.84,;56.35,-16.36,;56.03,-17.88,;57.17,-18.9,;56.85,-20.41,;55.38,-20.89,;54.23,-19.86,;54.56,-18.35,;46.11,-22.42,;47.01,-23.65,;46.38,-25.04,;47.27,-26.28,;48.79,-26.12,;49.41,-24.71,;48.51,-23.49,;49.12,-22.09,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NAD				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01264 BindingDB Entry DOI: 10.7270/Q21R6VDH
					More data for this Ligand-Target Pair