null

SMILES: OC(=O)c1cnc(SCC2CCCCC2)[nH]c1=O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50580322   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha inhibitor (Homo sapiens (Human))	BDBM50580322 (CHEMBL5072902) Show SMILES OC(=O)c1cnc(SCC2CCCCC2)[nH]c1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FIH using HLEVVKLLLEAGADVNAQDK-CONH2 as substrate preincubated for 15 mins followed by substrate addition and measured after 15 m...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00605 BindingDB Entry DOI: 10.7270/Q2GQ72N6
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2A (Homo sapiens (Human))	BDBM50580322 (CHEMBL5072902) Show SMILES OC(=O)c1cnc(SCC2CCCCC2)[nH]c1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal His6-tagged KDM2A (M1 to P517 residues) expressed in insect cells using H3K36(Me2) as substrate preincubated for 15 mi...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00605 BindingDB Entry DOI: 10.7270/Q2GQ72N6
					More data for this Ligand-Target Pair
Lysine-specific demethylase 3B (Homo sapiens (Human))	BDBM50580322 (CHEMBL5072902) Show SMILES OC(=O)c1cnc(SCC2CCCCC2)[nH]c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00605 BindingDB Entry DOI: 10.7270/Q2GQ72N6
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50580322 (CHEMBL5072902) Show SMILES OC(=O)c1cnc(SCC2CCCCC2)[nH]c1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human KDM6B (D1141 to R1641 residues) expressed in Escherichia coli using H3K27(Me3) as substrate preincubated for 15 mins followed by ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00605 BindingDB Entry DOI: 10.7270/Q2GQ72N6
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4D (Homo sapiens (Human))	BDBM50580322 (CHEMBL5072902) Show SMILES OC(=O)c1cnc(SCC2CCCCC2)[nH]c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal His6-tagged KDM4D (M1 to G373 residues) expressed in Escherichia coli using H3K9(Me3) as substrate preincubated for 15...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00605 BindingDB Entry DOI: 10.7270/Q2GQ72N6
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM50580322 (CHEMBL5072902) Show SMILES OC(=O)c1cnc(SCC2CCCCC2)[nH]c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal His6-tagged KDM5B (L882 to S1761 residues) expressed in insect cells using H3K4(Me3) as substrate preincubated for 15 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00605 BindingDB Entry DOI: 10.7270/Q2GQ72N6
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4A (Homo sapiens (Human))	BDBM50580322 (CHEMBL5072902) Show SMILES OC(=O)c1cnc(SCC2CCCCC2)[nH]c1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal His6-tagged KDM4A (M1 to L359 residues) expressed in Escherichia coli using H3K9(Me3) as substrate preincubated for 15...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00605 BindingDB Entry DOI: 10.7270/Q2GQ72N6
					More data for this Ligand-Target Pair