null
SMILES: CN(Cc1sc(nc1C)-c1ccc(cc1)C(F)(F)F)c1ccc(\C=C\C(O)=O)cc1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM50580367 (CHEMBL5076771) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 947 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human PPARalpha transfected in COS-7 cells assessed luciferase activity measured after 24 hrs by cell based luciferase transactiv... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00560 BindingDB Entry DOI: 10.7270/Q2Q81HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50580367 (CHEMBL5076771) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.47E+4 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human PPARgamma transfected in COS-7 cells assessed luciferase activity measured after 24 hrs by cell based luciferase transactiv... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00560 BindingDB Entry DOI: 10.7270/Q2Q81HXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM50580367 (CHEMBL5076771) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 199 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human PPARdelta transfected in COS-7 cells assessed luciferase activity measured after 24 hrs by cell based luciferase transactiv... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00560 BindingDB Entry DOI: 10.7270/Q2Q81HXK | |||||||||||
More data for this Ligand-Target Pair |