null

SMILES: COc1cc(C)c2[nH]cc(\C=N\NC(=N)NCCc3ccc(cc3)C#N)c2c1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50581009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Relaxin-3 receptor 1 (Homo sapiens (Human))	BDBM50581009 (CHEMBL5094670) Show SMILES COc1cc(C)c2[nH]cc(\C=N\NC(=N)NCCc3ccc(cc3)C#N)c2c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	268	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [125I]R3/I5 from human RXFP3 expressed in human CHO-K1 cells incubated for 1 hr by microplate scintillation counting analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01081 BindingDB Entry DOI: 10.7270/Q2ZK5MJP
					More data for this Ligand-Target Pair
Relaxin-3 receptor 1 (Homo sapiens (Human))	BDBM50581009 (CHEMBL5094670) Show SMILES COc1cc(C)c2[nH]cc(\C=N\NC(=N)NCCc3ccc(cc3)C#N)c2c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human RXFP3 expressed in human CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 1.5 hrs ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01081 BindingDB Entry DOI: 10.7270/Q2ZK5MJP
					More data for this Ligand-Target Pair