null
SMILES: C[C@H](NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)CCSCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](OP(O)(O)=O)[C@@H]1O)n1cnc2c(N)ncnc12)C(N)=O
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N-alpha-acetyltransferase 40 (Homo sapiens) | BDBM50581151 (CHEMBL5077510) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human NatD using H4-8 peptide substrate at Km value and AcCoA by Morrison's quadratic equation analysis | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00141 BindingDB Entry DOI: 10.7270/Q2XK8KFR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-alpha-acetyltransferase 40 (Homo sapiens) | BDBM50581151 (CHEMBL5077510) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human NatD using H4-8 peptide substrate at Km value and AcCoA measured after 30 min incubation by fluorescence assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00141 BindingDB Entry DOI: 10.7270/Q2XK8KFR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-alpha-acetyltransferase 40 (Homo sapiens) | BDBM50581151 (CHEMBL5077510) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human NatD using H4-8 peptide substrate at 4 times Km value and AcCoA measured after 30 min incubation by fluorescence assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00141 BindingDB Entry DOI: 10.7270/Q2XK8KFR | |||||||||||
More data for this Ligand-Target Pair |