null
SMILES: COc1cc(ccc1OCCc1ccnc(N)c1)N(C1CCN(C)CC1)C(=O)NCCCn1cncc1C
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human)) | BDBM50581435 (CHEMBL5089539) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113819 BindingDB Entry DOI: 10.7270/Q2M61Q44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutaminyl-peptide cyclotransferase (Mus musculus (mouse)) | BDBM50581435 (CHEMBL5089539) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of mouse QPCT measured after 15 mins by fluorimetry | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113819 BindingDB Entry DOI: 10.7270/Q2M61Q44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutaminyl-peptide cyclotransferase-like protein (Homo sapiens (Human)) | BDBM50581435 (CHEMBL5089539) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of isoQC (unknown origin) | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113819 BindingDB Entry DOI: 10.7270/Q2M61Q44 | |||||||||||
More data for this Ligand-Target Pair |